[Interferon gamma based tests as a new tool in diagnosis of latent tuberculosis].
نویسنده
چکیده
منابع مشابه
مروری بر روش‌های تشخیص ایمونولوژیک عفونت سل
Tuberculosis (TB) is a leading cause of mortality and morbidity in the world and this infection is a major public health challenge. TB control is largely dependent on the early diagnosis and managements of suspected cases. Today, for laboratory diagnosis of TB infection, several bacteriological and immunological methods such as sputum smear microscopy, sputum culture and tuberculin skin test ar...
متن کاملThe Use of Interferon Gamma Release Assays in the Diagnosis of Active Tuberculosis
Interferon gamma release assays (IGRAs) are in vitro immunologic diagnostic tests used to identify Mycobacterium tuberculosis infection. They cannot differentiate between latent and active infections. The cutoff suggested by the manufacturer is 0.35 IU/mL for latent tuberculosis. As IGRA tests were recently approved for the differential diagnosis of active tuberculosis, we assessed the diagnost...
متن کاملDiagnosis of latent tuberculosis infection: the potential role of new technologies.
Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. TB control programmes need improvement in the diagnosis of latent TB infection. The tuberculin skin test (TST) is far from a 'gold' standard as it often gives false results. Interferon-gamma assays are newly available tests to detect latent TB infection, but they are currently not routinely used. They are based on immune r...
متن کاملLevel of Interferon Gamma in the Blood of Tuberculosis Patients
Background: Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M. tuberculosis. It activates the production of other cytokines and molecules that kill mycobacterium. IFN-γ also has diagnostic role in identification of active and latent tuberculosis. Objective: To determine the level of IFN-γ in the blood of TB patients. Methods: Ninety...
متن کاملعفونت سل نهفته در کارکنان مراکز درمانی: مقاله مروری
The members of Mycobacterium tuberculosis complex (MTBC) known as causative agents of human tuberculosis. Tuberculosis infection is one of the most important occupational risks for healthcare workers (HCWs) in most countries, such as Iran. In general, there are two types of tuberculosis, they include: latent infection and active TB. Latent tuberculosis infection (LTBI) means: a patient is infec...
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ورودعنوان ژورنال:
- Pneumonologia i alergologia polska
دوره 79 4 شماره
صفحات -
تاریخ انتشار 2011